Life Sciences: Adverse Event Triage with Codex: Sandbox Policy
A production playbook for adverse event triage in life sciences operations using Codex: sandbox policy, run-scoped inputs, logs, typed results, and artifacts.
Audience: Pharmacovigilance teams
The problem
Pharmacovigilance teams need adverse event triage to run repeatedly against case narratives, intake forms, medical history, and reporting rules. In life sciences operations, the pain is not one good answer; it is repeatability, auditability, exception handling, and evidence that survives handoff.
Implementation path
Run adverse event triage in an ephemeral sandbox, keep provider credentials in the broker, expose narrow tools, and store logs outside the workspace for review.
Tradeoffs and failure modes
A narrower runtime blocks ambient machine behavior, but it gives security reviewers a concrete boundary. For adverse event triage, the practical test is whether a second run can be debugged, retried, and consumed by a product without reading the raw agent transcript.
Runtime boundary
filesystem: /skill and /skill/.argo/inputs only
network: deny by default
artifacts: /skill/output/artifacts
logs: retained outside sandbox
provider: Codex
Run this on Argo